摘要
目的研究苗药马兰的化学成分。方法利用Sephadex LH-20,硅胶柱色谱和硅胶制备薄层色谱等分离方法反复分离纯化,用各种波谱数据分析鉴定化合物的结构。结果从马兰的乙醇提取部分分离得到6个化合物,分别鉴定为木栓酮(Ⅰ),木栓醇(Ⅱ),达玛二烯醇乙酸酯(Ⅲ),月桂酸(Ⅳ),β-谷甾醇(Ⅴ),脱镁叶绿甲酯酸(Ⅵ)。结论化合物Ⅰ~Ⅵ均首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents in Kalimeris indica(L.) Sch-Bip.METHODS Compounds were separated and purified by column chromatography,preparative TLC silica gel and Sephadex LH-20,and their structures were elucidated by chemical and spectral analysis(NMR,IR,UV,and MS).RESULTS Six compounds were obtained.Their structures were characterized as mominine(Ⅰ),friedelan-3-ol(Ⅱ),dammaradienyl acetate(Ⅲ),lauric acid(Ⅳ),β-sitosterol(Ⅴ) and methyl phaeophorbide(Ⅵ);respectively.CONCLUSION All compounds are obtained from this plant for the first time.
关键词
马兰 /
化学成分 /
菊科
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Key words
Kalimeris indica(L.) Sch-Bip
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林材;曹佩雪;梁光义 .
马兰化学成分的研究[J]. 中国药学杂志, 2006, 41(04): 251-252
LIN Ci;CO Pei-xue;LING Gung-yi;.
Studies on Chemical Constituents of Kalimeris indica[J]. Chinese Pharmaceutical Journal, 2006, 41(04): 251-252
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参考文献
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脚注
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基金
贵州省中药现代化专项资金资助项目[黔科合中药专字(2003)07号]
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