泥胡菜化学成分研究

邹忠杰;鞠建华;杨峻山

中国药学杂志 ›› 2006, Vol. 41 ›› Issue (02) : 102-103.

中国药学杂志 ›› 2006, Vol. 41 ›› Issue (02) : 102-103.
论著

泥胡菜化学成分研究

  • 邹忠杰;鞠建华;杨峻山
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Studies on Chemical Constituents of Hemistepta lyrata

  • ZOU Zhong-jie, JU Jian-hua, YANG Jun-shan
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摘要

目的研究泥胡菜的化学成分。方法泥胡菜全草体积分数为95%乙醇提取物的氯仿和乙酸乙酯部分进行色谱分离, 根据光谱数据和理化性质确定各化合物的结构。结果分离得到9种已知成分,分别为金合欢素(1);β-谷甾醇(2);山柰素 (3);胡萝卜苷(4);金合欢素-7-O-β-D-葡萄糖苷(5);水杨酸(6);山柰素-3-O-β-D-葡萄糖苷(7);金合欢素-7-O-β-D-芦丁糖苷 (8);琥珀酸(9)。结论化合物3,5,6和9为首次从本属植物中分离得到。

Abstract

OBJECTIVE To investigate the chemical constituents of Hemistepta. lyrata.METHODS The constituents of the CHCl3-sol-uble and EtOAc-soluble portions of the 95% ethanol extraction were isolated and purified by means of chromatography. Compounds were identified by their physical characteristics and spectral features. RESULTS Nine compounds were isolated and identified as acacetin(1); β-sitos-terol(2);kaempferol (3) ;daucossterol(4) ;acacetin-7-O-β-D-glucoside (5);salicylic acid(6);kaempferol-3-O-β-D-glucoside (7);acacetin-7-O-β-D-lutinoside (8) and succinic acid (9) .CONCLUSION Compound 3,5,6 and 9 are isolated from this genus for the first time.

关键词

泥胡菜 / 化学成分

Key words

Hemistepta lyrata

引用本文

导出引用
邹忠杰;鞠建华;杨峻山. 泥胡菜化学成分研究[J]. 中国药学杂志, 2006, 41(02): 102-103
ZOU Zhong-jie;JU Jin-hu;YNG Jun-shn. Studies on Chemical Constituents of Hemistepta lyrata[J]. Chinese Pharmaceutical Journal, 2006, 41(02): 102-103

参考文献

[1] Jiangsu New Medical College. Dictionary of Chinese Materia Medica(中药大辞典)[M] .Shanghai: Shanghai Scientific and Technical Publisher,1986: 1458. [2] QU G R,LIU J,LI X X,et al. Studies of flavones in sonchus arvensis [J] .Chin Tradit Herb Drugs(中草药),1995,26(5):233-235. [3] GONG Y H.13C-NMR Chemical Shift of Natural Organic Compounds(天然有机化合物的13C核磁共振化学位移) [M] .Kunming:Yunnan Science and Technique Press,1986:157. [4] LIU J Q,SHEN Q Q,LIU J S,et al. Studies on the chemical constituents from Chrysanthemum morifolium[J] .China J Chin Mater Med(中国中药杂志),2001,26(8):547-548. [5] LIN L D,QIN G W,XU R S. Studies on the chemical constituents of Ilex centrochinese[J] .Acta Bot Sin(植物学报),1994,36(5): 393-397. [6] REN Y L,YANG J S. Chemical constituents of Hemistepta lyrata[J] .Acta Pharm Sin(药学学报),2001,36(10): 746-749.

基金

国家自然科学基金青年科学基金(20202014)博士点基金(20020023001)

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