棕菊合剂抗实验性前列腺炎的研究

叶加;刘晓岩;蒋益民;李长龄

中国药学杂志 ›› 2005, Vol. 39 ›› Issue (08) : 586-588.

中国药学杂志 ›› 2005, Vol. 39 ›› Issue (08) : 586-588.
论著

棕菊合剂抗实验性前列腺炎的研究

  • 叶加;刘晓岩;蒋益民;李长龄
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Study on effect of mixture of Serenoq repens and Echinacea purpurea against experimental prostatitis in rats

  • YE Jia1, LIU Xiao-yan1,JIANG Yi-min2,LI Chang-ling1
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摘要

目的观察棕菊合剂(MSE)对大鼠实验性前列腺炎的治疗作用。方法用消痔灵注射液致大鼠慢性前列腺炎症模型和巴豆油致大鼠急性前列腺炎症模型,观察MSE药抗前列腺炎症的作用,每日给MSE 30,60,120 mg·kg-1,ig,连续21 d和14 d,以吾真宁(Urgenin)作阳性对照,蒸馏水作模型对照。结果发现用MSE后,消痔灵致大鼠慢性前列腺炎症和巴豆油致大鼠急性前列腺炎症的前列腺重量均有不同程度的减轻;光学显微镜显示,腺腔内炎症细胞浸润程度及纤维母细胞增生程度均有所减轻。较对照组有显著差异(P<0.05)。结论表明MSE有明显抑制实验性前列腺炎症的作用。

Abstract

OBJECTIVE To study the effect of MSE (mixture of Serenoa repens and Echinacea purpurea)on experimental prostatitis in rats.METHODS The prostatitis models induced by Dispel piles injection and by croton oil in rats were treated with MSE 30,60,120 mg·kg-1·d-1, ig for 21 and 14 d, respectively.RESULTS The weight of prostate and the proliferation degree of prostatitis were obviously decreased , compared with model group (P< 0.05). CONCLUSION MSE could obviously inhibit experimental prostatitis in rats.

关键词

棕菊合剂 / 实验性前列腺炎

Key words

mixture of Serenon repens and Echinacea purpwea / experimental prostatitis

引用本文

导出引用
叶加;刘晓岩;蒋益民;李长龄. 棕菊合剂抗实验性前列腺炎的研究[J]. 中国药学杂志, 2005, 39(08): 586-588
YE Ji;LIU Xio-yn;JING Yi-min;LI Chng-ling. Study on effect of mixture of Serenoq repens and Echinacea purpurea against experimental prostatitis in rats [J]. Chinese Pharmaceutical Journal, 2005, 39(08): 586-588

参考文献

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