中药地菍黄酮类成分的分离与鉴定

张超;方岩雄

中国药学杂志 ›› 2003, Vol. 38 ›› Issue (04) : 256-258.

中国药学杂志 ›› 2003, Vol. 38 ›› Issue (04) : 256-258.
中药及天然药物

中药地菍黄酮类成分的分离与鉴定

  • 张超;方岩雄
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Studies on the flavonoids constituents of Chinese herb Melastoma dodecandrum

  • ZHANG Chao1,FANG Yan-xiong2
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摘要

目的对地菍(Melastoma dodecandrum Lour)全草的化学成分进行分离鉴定。方法溶剂萃取及各种色谱技术分离纯化,经UV,IR,1H-NMR,13C-NMR,MS以及化学方法鉴定了它们的结构。结果分离得到7个化合物,分别是木犀草素(Ⅰ)、木犀草素-7-O-β-葡萄糖苷(Ⅱ)、木犀草素-7-O-β-半乳糖苷(Ⅲ)、槲皮素(Ⅳ)、槲皮素-3-O-β-葡萄糖苷(Ⅴ)、槲皮素-3-O-β-半乳糖苷(Ⅵ)、广寄生苷(Ⅶ)。结论这些成分均为首次从该植物中获得。

Abstract

OBJECTIVE To separate and identify the chemical constituents of the whole plant of chinese herb -Melastoma Dodecandrum- Lour.METHOD S The flavonoid constituents were isolated by solvent extraction and chromatography.Their chemical structures were identified on the basis of physicchemical constant and spectral data.RESULTS Seven compounds were isolated and identified as luteolin (Ⅰ),luteolin-7-O-β-glucoside (Ⅱ),luteolin-7-O-β-galactoside (Ⅲ),quercetin (Ⅳ),quercetin-3-O-β-glucoside (Ⅴ),quercetin-3-O-β-galactoside (Ⅵ) and avicularin (Ⅶ).CONCLUSION The abovementioned compounds were separated from the plant for the first time.

关键词

地菍 / 木犀草素 / 木犀草素-7-O-β-半乳糖苷 / 广寄生苷

Key words

Melastoma dodecandrum Lour / luteolin / quercetin / quercetin-3-O-β-galactoside / avicularin

引用本文

导出引用
张超;方岩雄. 中药地菍黄酮类成分的分离与鉴定[J]. 中国药学杂志, 2003, 38(04): 256-258
ZHNG Cho;FNG Yn-xiong. Studies on the flavonoids constituents of Chinese herb Melastoma dodecandrum[J]. Chinese Pharmaceutical Journal, 2003, 38(04): 256-258

参考文献

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