［1］付良青，吴德政.细胞色素P4502D6的研究进展［J］.中国临床药理学杂志.2000，16(6)：453. ［2］鞠美华.细胞色素P450同工酶在外源物代谢中的作用［J］.国外医学·药学分册，1998,25(4)：218. ［3］Pollenz RS.The ary-hydrocarbon receptor nuclear translocator protein is rapidly depleted in hepatic and nonhepatic culture cells exposed to 2,3,7,8-tetrachlordibenzo-p-dioxin［J］.Mol Pharmacol,1996,49(3):391. ［4］Xu L,Li AP,Kaminski DL,et al.2,3,7,8-Tetrachlordibenzo-p-dioxin inducti-on of cytochrome P4501A in cultured rat and human hepatocytes［J］.Chem Biol Interact,2000,124(3):173. ［5］Moorthy B.Persistent expression of 3-methylcholanthrene-inducible cytochromes P4501A in rat hepatic and extrahepatic tissues ［J］.J Pharmacol Exp Ther,2000,294(1):313. ［6］Degawa M,Nakayama M,Konno Y,et al.2-Methoxy-4-nitroaniline and its isomers induce cytochrome P4501A(CYP1A) enzymes with different selectivities in the rat liver［J］.Biochim Biophys Acta,1998,1379(3):391. ［7］Klenam MI,Overvik E,Poellinger L,et al.Induction of cytochrome P4501A isozymes by heterocyclic amines and other food-derived compounds［J］.Princess Takamatsu Symp,1995,23:163. ［8］Iba MM,Scholl H,Fung J,et al.Induction of pulmonary CYP1A1 by nicotine［J］.Xenobiotica,1998,28(9):827. ［9］Chen RM,Chou MW,Ueng TH.Induction of cytochrome P4501A in hamster liver and lung by 6-nitrochrysene［J］.Arch Toxicology,1998,72(7):395. ［10］Gwang JH.Induction of rat hepatic cytochrome P4501A and P4502B by the methoxsalen［J］.Cancer Lett,1996,109(1-2):115. ［11］Stadler J,Trockfeld J,Schmalix WA,et al.Inhibition of cytochromes P4501A by nitric oxide［J］.Proc Natl Acad Sci USA,1994,91(9):3559. ［12］Degawa M,Mikami K,Naniki M.et al.Inhibition of the induction and activity of hepatic P4501A isozymes by in vivo［J］.Biol Pharm Bull,1993,16(12):1248. ［13］Bruschweiler BJ,Wurjler FE,Fent K.Inhibitory effect of heavy metals on cytochrome P4501A induction in permanent fish hepatoma cells［J］.Arch Environ Contam Toxicol,1996,31(4):475. ［14］Takahashi N,Dashwood RH,Bjeldanes LF,et al.Regulation of hepatic cyto-chrome P4501A by indole-3-carbinol:transient induction with continuous feeding in rainbow trout［J］.Food Chem Toxicol,1995,33(2):111. ［15］周宏灏.遗传药理学［M］.北京：科学出版社，2001：82. ［16］Distlerath LM,Reilly PE,Martin MV,et al.Purification and charactcrization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-dccthylation,two prototypcs for genetic polymorphism in oxidative drug metabolism［J］.J Biol Chem,1985,25(15):9057. ［17］许振华，周宏灏.细胞色素氧化酶P4501A2与药物代谢［J］.中国临床药理学杂志， 1996,12(2):115. ［18］Berthou F,Goasduff T,Dreano Y,et al.Caffeine increases its own metabolism through cytochrome P4501A induction in rats［J］.Life Sci,1995,57(6):541. ［19］Davis JD,Aarons L,Houston JB.Metabolism of theophylline and its inhibition by Fluoroquinolones in rat hepatic microsomes［J］.Xenobiotica,1995,25(6):563. ［20］Ward SA,Walle T,Walle K,et al.Propranolol's metabolism is determined by both mephenytoin and debrisoquine hydroxylase activities［J］.Clin Pharmacol Ther,1989,45(1):72. ［21］Yoshimoto K,Echizen H,Chiba K,et al.Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers-N-desisopropylaton is mediated mainly by CYP1A2［J］.Br J Clin Pharmacol,1995,39(4):421. ［22］Rey-Grobellet X,Eeckhoutte C,Sutra JF,et al.Major involvement of rabbit liver cytochrome P4501A in thiabendazole 5-hydroxylation［J］.Xenobiotica,1996,26(7):765. ［23］Szotakova B,Wsol V,Skalova L,et al.Role of cytochrome P4501A in biotransformation of the potential anticancer drug oracin［J］.Exp Toxicol Pathol,1999,51(4-5):428. ［24］Beresford AP,Ellis WJ,Ayrton J,et al.Cytochrome P4501A(CYP1A) induction in rat and man by the benzodioxino derivative,fluparoxan［J］.Xenobiotica,1997,27(2):159. ［25］印绮平，奚念珠，王宏图，等.地尔硫对人体内安替比林代谢的选择性抑制作用研究［J］.中国药学杂志，1999,34(4):253. ［26］Kaminsky LS,Zhang ZY.Human P450 metabolism of warfarin［J］.Pharmacol Ther,1997,73(1):67. ［27］朱大岭.CYP1A1基因型与吸烟及肺癌的关系［J］.国外医学·卫生学分册，1996,23(2):96. ［28］张宏艳，孙长生，李良寿，等.细胞色素P4501A1与食管癌遗传易感性［J］.中华预防医学杂志,2000,34(2):69. ［29］刘希永，蔡善荣.代谢基因多态与大肠癌遗传易感性［J］.国外医学·肿瘤学分册,2000,27(1):61. ［30］王建，刘焯霖，陈彪.细胞色素P450酶基因多态性与帕金森病的关系［J］.中华医学杂志,2000,80(8):585.