[1]梁文权.药物在皮肤内的扩散.见:梁秉文主编.经皮给药制剂.北京:中国医药出版社,1992:37~39.
[2]Tayar NE,Tsai RS,Testa B,et al.Percutaneous penetration of drugs:a quantitative structure-permeability relationship study.J
Pharm Sci,1991,80(8):744.
[3]Cohen MH,Turnbull D.Molecular transport in liquids and gases.J Chem Phys,1959,31(5):1164.
[4]Potts RO,Guy RH.Predicting skin permeability.Pharm Res,1992,9(5):663.
[5]Abraham MH,Martins F,Mitchell RC.Algorithms for skin per-meability using hydrogen bond descriptors: the problem of
steroids.J Pharm Pharnracol,1997,49:858.
[6]Lien EJ,Gao H.QSAR analysis of skin permeability of various drugs in man as compared to in vivo and in vitro studies in ro-
dents.Pharm Res,1995,12(4):583.
[7]Wilson LY.Using theoretical descriptors in quantitative struc-tune-activity relationships: Some toxicological indices.J Med
Chem,1991,34:1668.
[8]Dewar MJS,Zoebisch EG,Healy EF,et al.AMI:Anew general purpose quantum mechanical molecular model.J Am Green Sa,
1985,107:3902.
[9]商志才,俞庆森,林瑞森,Van der Waals分子体积及表面积的 Monte Carlo模拟计算.物理化学学报,1997,12:1097.
[10]Pons RO,Guy RH.A predictive algorithm for skin permeability:the effects of molecular size and hydrogen bond activity.Pharrn
Res,1995,12:1628.