OBJECTIVE: To study the effect of ginsenoside to the gastrocolic cancer cells. METHODS: The drug sensitivity to the cancer tissues from 38 cases of gastric carcinoma and 40 cases of colonic carcinoma has been made with a method of thiazole blue the determination (MTT).The drug sensitivity test involved ginsenoside and 8 kinds of common chemotherapeutic agents. RESULTS: Ginsenoside to colonic carcinoma was more sensitive in comparison with the gastric carcinoma.Its effect was obviously low than 5FU(fluorouracil),DDP(cis diaminedichloroplatin),MMC(mitomycine),PYM(ping yang mycin),TSPA(triethylenethiophosphoramide),VP16(vepeside). CONCLUSION: Ginsenoside as a adjuvant can be combined with some chemotherapeutic agents for the treatments of gastric and colonic carcinoma.