1 Junginger HE, Hofland HE, Bouwstra JA. Liposomes and nisomes: interactions with human skin. Cosmet Toilet,1991,106:45. 2 Roiling J, Ghyczy M. Control of skin humidity with liposoms and stabilization of skin care oils and lipophilic active substances with liposomes. SOFW, 1991,10:372. Mezei M. Gulasekharam V. Liposomes——a selective drug delivery system for the topical route of administration: gel dosage form. J Pharm Pharmacol, 1982,34:473. 4 Cevc G, Blume G. Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force. Biochim Biophys Acta, 1992,1104:226. 5 Ghyczy M. Chemical composition of liposomes and its influence on the humidity of normal skin. In: Braun-Falco O,Korting HC, Maibach HI eds. Liposome Dermatics. Berlin:Springer-Verlag, 1992: 308一314. 6 Egbaria K, Weiner N. Topical delivery of liposomally encapsulated ingredients evaluated by in vitro diffusion studies. In: Braun-Falco O, Korting HC, Maibach HI, eds. Liposome Dermatics. Berlin: Springer-Verlag, 1992:172～181. 7 Bodde HE, Pechtold LARM, Subnel MTA, et al. Monitoring in vivo skin hydration by liposome using infrared spectroscopy in conjunction with tape stripping. In: Braun-Falco O, Korting HC, Maibach HI eds. Liposome Dermatics. Berlin: Springer-Verlag, 1992:137～149. 8 Bouwstra JA, Hofland HE, Spies F, et al.Changes in the structure of the human stratum corneum induced by liposomes. In: Braun-Falco O, Korting HC, Maibach HI eds. Liposome Dermatics. Berlin: Springer-Verlag, 1992:121～136. 9 Roding J, Artmann C. The fate of liposomes in animal skin. In: Braun-Falco O, Korting HC, Maibach HI eds. Liposome Dermatics. Berlin: Springer-Verlag, 1992:185～194. 10 Schmid MH. The fate of liposomes for topical use in skin tissue culture. In: Braun-Falco O, Korting HC, Maibach HI eds. Liposome Dermatics.Berlin: Springer-Verlag,1992:195～199. 11 Blume G, Jansen M, Ghyczy M, et al.Interaction of phospholipid liposomes with lipid model mixtures for stratum corneum lipid. Int J Pharm, 1993,99:219. 12 Surleve-Bazeille JE, Mercier M, Lemenn R. Cryofracture study of the lamellar structure of the intercellular lipids of human stratum corneum after topical application of ceramides. Int J Cosmet Sci, 1993,15(3):101. 13 Sebastian Z, Wolfgang P, Juergen L. Interaction of phosphatidylcholine liposomes and the human stratum corneum. Bzochim Biophys Acta, 1995,1237(2):176. 14 Koding J. Liposomes. SOFW. 1990,14:509. 15 Artmann C, Roding J, Ghyczy M, et al. Liposomes from soya phospholipids as percutaneous drug carrier. Drug Res,1990, 40(12):1363. 16 Mezei M. Biodisposition of liposome-encapsulated active ingredients applied on the skin. In: Braun-Falco O, Korting HC, Maibach HI eds. Liposome Dermatics .Berlin: Springer-Verlag, 1992: 206～214. 17 Gehring W, Klein M, Gloor M. Influence of various topical liposome preparations with and without active ingredients on the cutaneous blood flow. In: Braun-Falco O, Korting HC, Maibach HI eds. Liposome Dermatics. Berlin: Springer-Verlag, 1992: 315. 18 Weiner H, Egbaria K, Ramachandran C. Topical delivery of liposomally encapsulated interferon evaluated by in vitro diffusion studies and in a cutaneous herpes guinea pig model. In: Braun-Falco O, Korting HC, Maibach HI eds.Liposome dermatzcs. Berlin: Springer-Verlag,1992:242. 19 Sharma BB, Jain SK, Sagar SP. Topical liposome system bearing local anesthetic lignocaine: preparation and evaluation. J Microencapsulation.1994,11(3):279 20 Fleisher O, Niemiec SM. Topical delivery of growth hormone releasing peptide using liposomal system: an in vitro study using hairless mouse skin. Life Sci, 1995,57(13):1293.