双膦酸盐治疗和预防绝经后骨质疏松症的研究进展

李庶心;王志清;胡文祥;

中国药学杂志 ›› 1997, Vol. 32 ›› Issue (02) : 65-68.

中国药学杂志 ›› 1997, Vol. 32 ›› Issue (02) : 65-68.
综述

双膦酸盐治疗和预防绝经后骨质疏松症的研究进展

  • 李庶心;王志清;胡文祥;
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摘要

目的:骨质疏松症的预防和治疗已成为当今社会老年医疗保健的一个非常重要的课题。双膦酸盐抑制骨吸收,用于防治绝经后骨质疏松症的研究发展迅速,为让大家了解这方面的国外进展情况作此综述。方法:本文从双膦酸盐的作用机制及临床上治疗、预防绝经后骨质疏松症三方面综述了主要的有关研究的进展,并作了展望。结果与结论:双磷酸盐的作用机制尚不完全清楚,以前认为直接作用于破骨细胞,新近则认为作用于成骨细胞。现有 研究表明:双膦酸盐安全有效,可用于临床上治疗和预防绝经后骨质疏松症。

关键词

骨质疏松症 / 双膦酸盐 / 作用机理 / 治疗作用

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李庶心;王志清;胡文祥;. 双膦酸盐治疗和预防绝经后骨质疏松症的研究进展[J]. 中国药学杂志, 1997, 32(02): 65-68

参考文献

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