摘要
目的:建立健神益智片的质量撞制方法。方法:用薄层层析法对其中的人参皂普和何首鸟进行定性鉴别,用比色法对其中的主要有效成分人参皂普进行了定量测定。萦外检浏波长为d 238 nm。结果:线性范围25~125 μg,平均回收率为100.39% (n=9),RSD为1.20%。结论:此方法中各阴性对照品均无干扰,含量测定方法灵敏度高,重现性好,可作为该制剂的质量控制标准。
Abstract
OBJECTIVE: A quality control method was established for Jianshen Yizhi Tablet (Chinese patent medicine). METHOD:Its ingrediets ginseng sopanin(GS) and Polygonum multiflorum thunb were identified by TLC. A colormetric method for determing GS,the main effective ingredients in the tablet,was established. Detecfive wavelength was 238 nm. RESULTS:The method was linear within the range of 25~125 pg,the average recovery was 100.39 % ,and the RSD was 1.21%.CONCLUSION :The method is sensitive and highly reproducible and it may be used for the quantitative determination of the tablet.
关键词
健神益智片 /
人参皂苷 /
何首乌 /
薄层色谱法
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Key words
Jianshen Yizhi tablet /
ginseng saponin /
Polygonum multiflorum /
TLC
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丁玉玲;程军;侯丽娟;李亮涛;马淑贤;霍玉书.
健神益智片质量控制方法的研究[J]. 中国药学杂志, 1996, 31(12): 743-745
Ding Yuling.
Quality control of Jianshen Yizhi Tablet[J]. Chinese Pharmaceutical Journal, 1996, 31(12): 743-745
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参考文献
1章观德,周志华,王慕邹,等.人参的分析Ⅰ—Ⅳ.药学学报,1980,15(3):175.
2邵春杰,徐景达.薄层扫描法和比色法测定人参皂贰的含量.中草药,1982.13(8):19.
3王乃利,徐绥绪,李冰,等.人参皂贰含量测定方法的比较研究.沈阳药学院学报,1985,2(4):288.
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脚注
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