小鼠口服SOD（superoxidedismutase，超氧化物歧化酶）后，在胃肠道进行吸收。对SOD经胃及肠道中的失活作用，包括胃酸和蛋白水解酶作用后活力的变化进行了测定。实验证明：SOD在胃酸中作用120min，残存活力为84．0％，由胃蛋白酶酶解120min，残在活力为82．3％，胰酶酶解210min，残存活力为83．1％。结果说明，SOD对模拟胃肠道中的变性作用有较强的耐受力，为SOD的口服提供理论依据。

SOD(superoxide dismutase)is absorpted in rat stomach and small intestines after itis taken orally.The inactivating effects on SOD,includirig hydrochloric acid in stomach and pro-teinases in stomach and small intestines,are measured. The remaining activities of SOD were84.0%in the hydrochloric acid reacting for 120 minutes,82.3%in the solution of pepsin reactingfor the same time and 83.1%in the solution of pancreatin reacting for 210 minutes。 The resultdemonstrates that SOD has strong resistance to the inactivating effects of imitated stomach andsmall intestines.