宽叶羌活化学成分的研究

杨秀伟;严仲鍵;频哲明;周光春;服部征雄;难波恒雄

中国药学杂志 ›› 1994, Vol. 29 ›› Issue (03) : 141-143.

中国药学杂志 ›› 1994, Vol. 29 ›› Issue (03) : 141-143.
中药及天然药物

宽叶羌活化学成分的研究

  • 杨秀伟;严仲鍵;频哲明;周光春;服部征雄;难波恒雄
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Chemical constituents of underground parts ofNotoptecygium forbesiiBoiss.

  • YANG Xiu-wei1;YAN Zhong-kai1;GU Zhe-ming2;ZHOU Guang-chun2;Masao Hattori ;Tsuneo Namba
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摘要

从宽叶羌活(NotopterygiumforbesiiBoiss.)的地下部分甲醇提取物中分得16个化合物。经理化常数和光谱分析,鉴定为佛手素、异前胡素、佛手内酯、cnidilin、p-hydroxyphenethylanisadte、demethylfuropinnarin、4-羟基-3,5-二甲氧基芪、notopterol、farcarineiol、反式阿魏酸、紫花前胡内酯、紫花前胡甙、佛手酚、6-氧-反式阿魏酰基紫花前胡甙、佛手酚-β-D-吡喃葡荡糖苷、β-谷甾醇-β-D-吡喃葡萄糖甙。其中,4-羟基-3,5-二甲氧基芪和farcarindiol系首次从该中药中分得。

Abstract

Sixteen constituents were isolated from underground parts of Notopterygium forbe-siiBoiss. Chemical evidence and spectra data analysis showed that they consist of bergamottin(1),isoimperatorin(2),bergapten(3),cnidilin(4),p-hydroxyphenethyl anisate(5),demethyl-furopinnarin(6),4'-hydroxy-3, 5-dimethoxystilbene(7),notopterol(8),farcarindiol(9),trans-fer-ulic acid(10),nodakenetin(11), nodakenin(12),bergaptol(13),6'-O-(trans-feruloyl) nodakenin(14),bergaptol-O-β-D-glucopyranoside(15),β-sitosteryl -O-β-D-glucopyranoside (16).

关键词

宽叶羌活 / 成分 / 4-羟基-3 / 5-二甲氧基芪 / farcarindiol

Key words

Notopterygium forbesii Boiss / constituents ^ 41-hydroxy-3 / 5-dimethoxystilbene / farcarindilo

引用本文

导出引用
杨秀伟;严仲鍵;频哲明;周光春;服部征雄;难波恒雄. 宽叶羌活化学成分的研究[J]. 中国药学杂志, 1994, 29(03): 141-143
YNG Xiu-wei;YN Zhong-ki;GU Zhe-ming;ZHOU Gung-chun;Mso Httori;Tsuneo Nm. Chemical constituents of underground parts ofNotoptecygium forbesiiBoiss.[J]. Chinese Pharmaceutical Journal, 1994, 29(03): 141-143

参考文献

1GU Zhe-ming,ZHANG De-xi,YANG Xiu-wei,et al.Isola-tion of two new coumarin glycosides from Notopterygium forbesii and evaluation of a Chinese crude drug,Qiang-Huo,the underground parts of N.incisum and N.forbesii,by highperfoumance liquid chromatography.Chem Pharm Bwll,1990,38(9);2498. 2YANG Xie-wei,GU Zhe-ming,WANG Ben-xiang,et al.Comparision of anti-lipid peroxidative effects of the under-ground parts of Notopterygium incisum and N.forbesii in mice.Planta Medica,1991,57(5);399. 3北川熏,吉川雅之,吉原实,他.生药修治0化学的解明(第1报)红参(Ginseng Radix Rubra)(7)含有成分j:Ol.药学杂志,1983,103;612. 4小泽贡,田中治.独活.羌活O化学成分.现代东洋医学,1987,8(2).69. 5Matsunaga H,Katano M,Yamamoto H et aL Studies on the panaxytriol of Panax ginseng C.A.Meyer,isolation,deter-mination and antitumor activity.Chem Pharm Bullf 1989,37(5);1279.

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