中国现代神经疾病杂志 ›› 2026, Vol. 26 ›› Issue (5): 457-462. doi: 10.3969/j.issn.1672-6731.2026.05.001

• 专论 • 上一篇    下一篇

2 脊髓电刺激术:从疼痛调控到神经功能修复

孟凡刚1,2,*(), 邓智怀2, 季玉陈2,*()   

  1. 1. 100070 北京市神经外科研究所 首都医科大学附属北京天坛医院神经外科学中心
    2. 450052 郑州大学第一附属医院神经外科
  • 收稿日期:2026-04-20 出版日期:2026-05-25 发布日期:2026-06-06
  • 通讯作者: 孟凡刚, 季玉陈
  • 基金资助:
    北京市高层次创新创业人才支持计划·登峰项目(G202512038); 河南省重点研发专项项目(241111310100)

Spinal cord stimulation: from pain modulation to neural function restoration

Fan-gang MENG1,2,*(), Zhi-huai DENG2, Yu-chen JI2,*()   

  1. 1. Beijing Neurosurgical Institute; Center of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
    2. Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, He'nan, China
  • Received:2026-04-20 Online:2026-05-25 Published:2026-06-06
  • Contact: Fan-gang MENG, Yu-chen JI
  • Supported by:
    Beijing High-Level Innovation and Entrepreneurship Talent Support Program(G202512038); Key Research and Development Program of He'nan(241111310100)

摘要:

慢性疼痛与神经功能障碍是神经系统疾病的重要致残原因,传统治疗方法对难治性病例疗效甚微。脊髓电刺激术通过脊髓局部回路重塑、脊髓上中枢网络调控及多系统神经修复介导多重神经调控与修复效应,以实现从疼痛调控到神经功能修复的跨越。但目前脊髓电刺激术在临床应用中仍存在许多未解决的问题,本文对其机制演进、技术与适应证进展等进行系统梳理,解析现存争议与挑战,探讨未来发展路径,以为脊髓电刺激术的临床规范化应用与科研创新提供参考。

关键词: 电刺激疗法, 脊髓, 疼痛, 运动障碍, 综述

Abstract:

Chronic pain and neurological dysfunction are important causes of disability in neurological diseases, and conventional treatments have limited efficacy for refractory cases. Spinal cord stimulation (SCS) has evolved from pain modulation to neurological function restoration, and can mediate multiple neuromodulatory and restorative effects by remodeling local spinal circuits, regulating supraspinal central networks and repairing multisystem neurological functions. However, numerous problems still exist in this field. This article systematically reviews the mechanistic evolution, technological progress and indication expansion of SCS, analyzes the current controversies and challenges in the field, explores future development paths, and provides references for the standardized clinical application and scientific innovation of SCS.

Key words: Electric stimulation therapy, Spinal cord, Pain, Motor disorders, Review

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