Chemical Constituents of n-Hexane Extract of Stigma Maydis
WANG Dan1,2,3, MA Yao-ling1, ZHAO Ying-nan1,2,3, ZHAO Ming1,2,3, WANG Wei-ming3,4, ZHANG Shu-jun1,2,3
1. Institute of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar 161006, China;
2. Heilongjiang Industrial Hemp Processing Technology Innovation Center, Qiqihar 161006, China;
3. Technology Innovation Center of Industrial Hemp for State Market Regulation, Qiqihar 161006, China;
4. Institute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China
OBJECTIVE To study the chemical constituents of stigma maydis. METHODSn-Hexane extraction, silica gel column chromatography, and HPLC were used for isolation and purification. The structure was identified by NMR spectrum analysis. RESULTS Twenty-four monomeric compounds were isolated from stigma maydis and identified as behenic acid(1), α-spinasterol(2), methyl linolenate(3), methyl linoleate(4), methyl stearate(5), methyl heneicosanoate(6), methyl heptadecanoate(7), hexadecanoic acid(8), stigmast-4,22-dien-3,6-dione(9), stigmast-4-en-3,6-dione(10), stigmasta-4,22-dien-3-one(11), simiarenol(12), 3β-hydroxy-5α,8α-epidioxyergosta-6,22-diene(13), 3β-hydroxystigmast-5,22-dien-7-one(14), 3β-hydroxystigmast-5-en-7-one(15), monoheneicosanoin(16), glyceryl monohexacosanoate(17), glyceryl monolinoleate(18), 1-O-hexadecanolenin(19), glyceryl monooleate(20), stigmast-5-en-3β,7α-diol(21), stigmast-4-en-3β,6β-diol(22), stigmast-4,22-dien-3β,6β-diol(23) and stigmast-4-en-3β,6α-diol(24). CONCLUSION Compounds 1-20 and 24 are isolated from the stigma maydis for the first time.
王丹, 马耀玲, 赵英楠, 赵明, 王伟明, 张树军. 玉米须正己烷萃取物化学成分研究[J]. 中国药学杂志, 2022, 57(22): 1881-1887.
WANG Dan, MA Yao-ling, ZHAO Ying-nan, ZHAO Ming, WANG Wei-ming, ZHANG Shu-jun. Chemical Constituents of n-Hexane Extract of Stigma Maydis. Chinese Pharmaceutical Journal, 2022, 57(22): 1881-1887.
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2022, Vol. 57 
