Abstract：OBJECTIVE To reconstruct the knowledge, beliefs and behaviors(knowledge, attitude, practice, KAP) model of safe medication, analyze the mechanism of action among various factors, and compare differences in different educational situations, and provide intervention basis for targeted improvement of women's safe medication level. METHODS Using the 2017-2020 database of the Chinese Association for Science and Technology “Smart Mother Action” project “Chinese Women's Drug Safety Behavior Risk KAP Survey Research”, one-way analysis of variance was used to explore the demographic characteristics of the difference in KAP levels, and the structural equation model is used to test the fit of the KAP model and explore the influencing factors of the KAP model, using multiple sets of structural equations to explore whether there are differences in the internal correlations of the latent variables under different education situations. RESULTS The knowledge score is( 27.88±6.36 )points(10-50), the attitude score is(15.19±5.03) points(6-30), and the behavior score is(35.22±7.75) points(10-50). There are statistical differences in knowledge, attitude and behavior scores in different places of residence. There are statistical differences in knowledge and attitude scores for different ages, education conditions and work conditions. In the structural equation model, the direct effect of knowledge on safe medication behavior is -0.128, while the indirect effect through attitude is 0.078, and the total effect of safe medication knowledge on safe medication behavior is -0.050. The direct effect of safe medication attitude on behavior is 0.154. The results of multiple sets of structural equations showed that the KAP models of different education levels were basically the same, and the structural weight test was inconsistent(Δχ2=386.71,Δdf=23, P＜0.01). The mechanism and path coefficient of the KAP model of safe drug use in different educational situations are statistically significant, but the intensity of action is different. CONCLUSION Insufficient knowledge and misunderstandings of behavior are important reasons for the hidden dangers of drug use among women in my country. Knowledge affects behavior through attitudes, and does not directly affect behavior. There are differences in the path coefficients between the latent variables of the KAP model of different education levels, so different KAP levels of safe medication should be improved for different education levels.
李轶凡, 冯欣, 马小磊, 王安妮, 刘正. 我国妇女人群安全用药知信行现况的多组结构方程模型分析[J]. 中国药学杂志, 2022, 57(12): 966-971.
LI Yi-fan, Feng Xin, MA Xiao-lei, WANG An-ni, LIU Zheng. A Multiple Structural Equation Model Analysis of the Current Situation of Safe Drug Use Among Chinese Women. Chinese Pharmaceutical Journal, 2022, 57(12): 966-971.
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2022, Vol. 57 
