Chemical Constituents from Gentiana hexaphylla Maxim. ex Kusnez.
LIU Yue1,3,4, SUN Xiao2,3, YANG Rui-rui3, GUO Yao-wu3*, MA Shuang-cheng4*
1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; 2. Xi′an Institute for Food and Drug Control, Xi′an 710054, China; 3. Shaanxi Institute for Food and Drug Control, Xi′an 710065, China; 4. National Institutes for Food and Drug Control, Beijing 100050, China
Abstract：OBJECTIVE To investigate the chemical components from Gentiana hexaphylla. METHODS The compounds were isolated by column chromatography with silica gel, Sephadex LH-20 and preparative HPLC. The structures were elucidated by the means of spectral data analysis. RESULTS Seventeen compounds were isolated, and their structures were determined as gentiopicroside (1), sweroside (2), swertiamarin (3), trifloroside (4), rindoside (5), rigenolides G (6), poacynose (7), vanillyl alcohol-4-O-β-D-glucopyranoside (8), isotachioside (9), tachioside (10), 1,5-bis (β-D-glucopyran osyloxy-2-(3′, 3′-dimethylallyl) benzene (11), coniferin (12), 5, 7, 3′, 4′-tetrahydroxy-8-C-β-D-glucopyranosyl flavone (13), vitexin (14), syringaresinol-4′-O-β-D-glucopy ranoside (15), pinoresinol-4-O-β-D-glucopyranoside (16), and adenosine (17). CONCLUSION Compounds 1-17 are isolated from this plant for the first time.
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LIU Yue, SUN Xiao, YANG Rui-rui, GUO Yao-wu, MA Shuang-cheng. Chemical Constituents from Gentiana hexaphylla Maxim. ex Kusnez.. Chinese Pharmaceutical Journal, 2020, 55(21): 1780-1786.
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2020, Vol. 55 
