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�й�ҩѧ��־ 2015, Vol. 50 Issue (6) :497-501    DOI: 10.11669/cpj.2015.06.007
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YUAN Lin1, HUANG Wen-zhong1*, LIANG De-qiang1, MA Yin-hai, DU Zhi-zhi2
1.Chemical Science and Technology Department, Kunming University, Kunming 650214, China;
2.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China

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Abstract�� OBJECTIVE To investigate the flavonoid glycosides in Clematis connata DC. METHODS Colum chromatography with different materials, such as RP-18, Sephadex LH-20 and silica gel, and semi preparative high performance liquid chromatography were used to isolate and purify the chemical constituents. Their structures were identified by spectroscopic analysis.RESULTS Eleven flavonoid glycosides were isolated and identified as kaempferol-3-O-��-D-glucopyranosyl methyl ester(1), isovitexin(2), kaempferol-3-O-��-D-glucopyranoside-7-��-L-rhamnopyranoside(3), kaempferol-3-O-��-L-rhamnopyranoside-7-��-L-rhamnopyranoside(4), kaempferol-3-O-��-L-(4-O-acetyl) rhamnopyranoside-7-��-L-rhamnopyranoside(5), kaempferol-3-O-(2-��-D-glucopyranosyl)-��-L-rhamnopyranoside-7-O-��-L-rhamnopyranoside(6), genistein-7-O-��-D-apiofuranosyl-(1��6)-O-��-D-glucopyranoside(7), lanceolarin(8), quercetin-3-O-��-D-(6��-n-butyl) glucuronide(9), quercetin-3-O-��-D-glucopyranosyl methyl ester(10), and isoorientin(11). CONCLUSION Compounds 1-11 are isolated from Clematis connata DC for the first time.
Keywords�� Clematis connata DC,   flavonoid glycoside,   kaempferol-3-O-��-D-glucopyranosyl methyl ester,   kaempferol-3-O-��-D-glucopyranoside-7-��-L-rhamnopyranoside     
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Ԭ��, ������*, ����ǿ�� .�ϱ��������л�ͪ���໯ѧ�ɷ��о�[J]  �й�ҩѧ��־, 2015,V50(6): 497-501
YUAN Lin-, HUANG Wen-Zhong-*, LIANG De-Qiang- etc .Study on the Flavonoid Glycosides from the Herb of Clematis connata DC[J]  Chinese Pharmaceutical Journal, 2015,V50(6): 497-501
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