Abstract��
OBJECTIVE To prepare indapamide sustained release capsules and investigate its release in vitro METHODS Blank pellets, hydrated magnesium silicate, hypromellose cellulose��triethyl citrate, Eudragit RL 100, Eudragit RS 100, Eudragit LS 55, etc, were used as materials to prepare indapamide sustained release capsules The content was determined by HPLC, and the effects of different solid weight gains of sustained release material on release of indapamide from capsules were evaluated by in vitro release test RESULTS The release in vitro of the sustained release pills met the requirements when the solid weight gain of the materials was 5.0% to 5.3% CONCLUSION The optimum preparation technique of indapamide sustained release capsules is established, which has guiding significance for the practical manufacture
LANG Yu-Jiao-,
ZHU Li-Qin-,
DONG Wei-Lin-*
.Preparation of Indapamide Sustained��release Capsules and Investigation of Its Release in Vitro [J] Chinese Pharmaceutical Journal, 2013,V48(24): 2134-2136
2013, Vol. 48 
