Abstract：OBJECTIVE To optimize the microwave processing technology of Farfarae Flos processed with Glycyrrhizae Radix et Rhizoma. METHODS On the basis of single factor test, the index was evaluated by overall normalized value of content of total alkaloid, coltsfoot ketone, rutin, isoquercitrin and alcohol extract, which were determined by UV and HPLC method, four factors (moist time, the dosage of Glycyrrhizae Radix et Rhizoma, fire and processing time) were studied by response surface methodology. The microwave processing technology of Farfarae Flos processed with Glycyrrhizae Radix et Rhizoma was optimized. RESULTS The optimal parameters of microwave processing technology were as follows: the moist time was 4.5 h, the dosage of Glycyrrhizae Radix et Rhizoma was 15%, the microwave power was 100%, the processing time was 83 s. The contents of total alkaloid, coltsfoot ketone, rutin, isoquercitrin and alcohol extract were 0.002 1%, 0.283 6%, 0.7%, 1.44% and 27.6%, respectively. CONCLUSION The optimized processing technology of Farfarae Flos processed with Glycyrrhizae Radix et Rhizoma is rational, stable and feasible, which can provide a theoretical basis for the industrial production.
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2020, Vol. 55 
