Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (2): 325-329.doi: 10.16352/j.issn.1001-6325.2022.02.011

• Mini Reviews • Previous Articles     Next Articles

Research progress on drug targets for anti-retinal and choroidal neovascular diseases

LIU Chen1, FANG Si-yin1, GU Cao1, WU Jin-hui2*   

  1. 1. Department of Ophthalmology, the First Affiliated Hospital, Navy Military Medical University, Shanghai 200433;
    2. Department of Ophthalmology, the Third Affiliated Hospital, Navy Military Medical University,Shanghai 200438, China
  • Received:2021-03-29 Revised:2021-08-13 Published:2022-01-24
  • Contact: * wjh2042@aliyun.com

Abstract: The appearance of new blood vessels in the neovascular age-related macular degeneration (nAMD), diabetic retinopathy (DR),and other ocular diseases is one of the important reasons for blindness. Anti-vascular endothelial growth factor (VEGF) drugs are the current mainstream. However, some patients have poor efficacy and other adverse reactions. There is still a need to develop new drugs.

Key words: retina, choroid, revascularization, drug targets

CLC Number: