基础医学与临床 ›› 2016, Vol. 36 ›› Issue (7): 1021-1025.
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赵欣1,申乐1,许力2,黄宇光3
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摘要: 糖尿病神经病理性疼痛和皮肤瘙痒症是糖尿病最常见的并发症。但是神经病理性疼痛和皮肤瘙痒症发病机制仍不清楚。本文讨论神经病理性疼痛和瘙痒可能的发病机制,包括高血糖引起的代谢紊乱、微血管病变、自身免疫等。
关键词: 糖尿病, 高血糖, 神经病变, 皮肤病变
Abstract: Diabetic neuropathic pain (DNP) and itch are the well-known complications of diabetes. Despite much advances in diabetes complications, the exact mechanisms of diabetic neuropathic pain and itch are still not clear. In this review, we discuss various possible mechanisms of the pathogenesis of neuropathic pain and itch, including the role of hyperglycemia in altering the physiology of peripheral nerves and other mechanisms of diabetic neuropathic pain and itch.
Key words: Diabetic, Hyperglycemia, Neuropathy, Skin lesions
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R363.1+3
赵欣 申乐 许力 黄宇光. 糖尿病与神经病理性疼痛和瘙痒[J]. 基础医学与临床, 2016, 36(7): 1021-1025.
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http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2016/V36/I7/1021