基础医学与临床 ›› 2016, Vol. 36 ›› Issue (1): 125-129.

• 短篇综述 • 上一篇    下一篇

免疫衰老与固有免疫细胞的相关研究进展

王敏   

  1. 内蒙古民族大学
  • 收稿日期:2015-05-19 修回日期:2015-07-20 出版日期:2016-01-05 发布日期:2015-12-29
  • 通讯作者: 王敏 E-mail:tl_wm@126.com

Correlation research on immunosenescence and cells of the innate immune system

  • Received:2015-05-19 Revised:2015-07-20 Online:2016-01-05 Published:2015-12-29

摘要: 免疫衰老是人类衰老进程中的一项重要生物学变化,主要特征是免疫功能下降导致的进行性免疫缺陷,对固有免疫和适应性免疫均有影响。其对人类固有免疫的影响机制尚不完全清晰。在衰老进程中,固有免疫细胞的功能、表面分子、细胞因子分泌及其信号转导等方面有改变。

关键词: 【关键词】免疫衰老 , 固有免疫, 细胞

Abstract: Immunosenescence is one of the most important biological changes occurring during human aging . It affects both innate and adaptive immunity . The impact of aging on innate immunity is less well understood particularly in humans. There are modifications in the number, surface molecules ,cytokines and signal transduction as well as the function of cells of the innate immune system during the ageing process.

Key words: 【Key words】Immunosenescence , Innate immunity, Cell