基础医学与临床 ›› 2013, Vol. 33 ›› Issue (2): 227-230.
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史雨晨,刘翠英,李俊发
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摘要： 缺血/低氧是临床许多疾病的病理生理过程之一，而miRNA-210以其在缺血/低氧状态下的稳定性和功能的多样性引起了人们广泛关注。本文分析了在缺血/低氧状态下miRNA-210对线粒体新陈代谢和血管生成的影响；并且进一步阐述了miRNA-210在心肌梗死，中风和肿瘤等缺血/低氧性损伤疾病中的作用。
关键词: 关键词：miRNA-210, 缺血/低氧性损伤, 癌症, 线粒体新陈代谢, 血管发生
Abstract: Ischemia/hypoxia is one of the common pathophysiological processes in many clinic diseases. The stabilities and diverse functions of miRNA-210 in ischemic / hypoxic state have been caused widespread concern. This article analyzes the effects of miRNA-210 on mitochondrial metabolism and angiogenesis in the ischemic / hypoxic state; then, attention is focus on the roles of miRNA-210 in ischemic / hypoxic diseases, such as myocardial infarction, stroke and cancer.
Key words: [Keywords] miRNA-210, ischemic/hypoxic injuries, cancer, mitochondria metabolism, angiogenesis
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中图分类号：R339.5
史雨晨 刘翠英 李俊发. 缺血/低氧相关疾病微小RNA-210的研究进展[J]. 基础医学与临床, 2013, 33(2): 227-230.
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http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2013/V33/I2/227
